A road traffic collision (RTC) on Tavistock Street has closed the road in both directions.
Bedfordshire Police and Bedfordshire Fire and Rescue are on the scene.
A statement from Bedfordshire Police said: “We were called at around 4.45pm this afternoon (Monday) to a report of a two-vehicle collision in Tavistock Street, Bedford.
“Emergency services are on the scene and we would advise motorists to avoid the area whilst we deal with the incident.”
The road is closed from The Crescent to Harpur Street with diversion in place.